Monitoring neuronal molecules during behaviour analytics

Date: Thursday 26 May 2016
Time:  3:00 PM - 4:30 PM
Location: Field Suite

Organizers: Jochen Klein (Goethe University, Frankfurt, Germany) and Gernot Riedel (Aberdeen University, UK)

Abstract:  While neuronal discharges are electrical, chemical molecules enable a great deal of modulation and fine tuning within brain circuits.  Neuronal signaling between nerve cells relies on the release, flux across the synaptic cleft and attachment of chemical neurotransmitters to specific receptors on the post-synaptic membrane.  These molecules can be measured using invasive techniques and, when measurements are performed in behavioural context, provide information about the transmitter systems involved and their relevance to behavioural change. In this symposium, we seek to bring together multiple ways of measurement of transmitter molecules when at the same time registering the behaviour of animals.  Microdialysis recording coupled to various analytical assessments are mapped onto behavioural recordings during normal behaviour or disease states and the symposium will include specialists with differential expertise.

Presentations

15:00 - 15:20  Microdialysis And Its Significance For Measuring Behaviour

Jochen Klein

Goethe University, Germany

15:20 - 15:40 NMDA receptor-dependent signaling in excitatory prefrontal neurons controls fear discrimination and fear extinction

Edward Korzus
University of California Riverside, United States of America

15:40 - 16:00  Amperometric Biosensors for Real-time Neurochemical Monitoring in Behaving Animals

John Patrick Lowry
Maynooth University, Ireland

16:00 - 16:30 Extra questions and discussion